UK (and other European) games will work fine on it. According to what I read, the systems are the same in Europe and in the US, so wireless should work also.
To charge it, you'll have to get a voltage converter (usually available for around $10).
http://www.amazon.co.uk/45W-USA-UK-Voltage-Converter/dp/B0007VZ6W4/ref=pd_bbs_sr_1/026-2941792-2799645?ie=UTF8&s=electronics&qid=1185877689&sr=8-1
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